Dr. Albert Banes is the President of Flexcell International Corporation in Hillsborough, NC, and Professor in the Joint Department of Biomedical Engineering at the University of North Carolina (UNC) at Chapel Hill and North Carolina State University. Dr. Banes has published 109 scientific articles and has 39 patents in his name. In 2007, Dr. Banes was elected as a Fellow of the American Institute for Medical Biological Engineering. Prior to joining the Biomedical Engineering faculty, Dr. Banes was a Professor in the Department of Orthopaedics at UNC for 10 years. Dr. Banes has worked in the field of Cytomechanics for over 20 years where he has developed enabling technology for research to mechanically stimulate cells in two- and three-dimensional culture via application of tensile strain, compression, and fluid shear stress.
He received his Ph.D. from Virginia Commonwealth University in Molecular Virology, his M.S. from the University of Richmond in Developmental Biology, and his B.A. from Lehigh University in Biology.
Some Related Publications:
- Qi J, Chi L, Bynum D, Banes AJ. Gap junctions in IL-1b-mediated cell survival response to strain. (2011) Journal of Applied Physiology. jap.00477.2010.
- Banes A, Banes AJ, Qi J, Dmochowski J, Bynum D, Schramme M, Patterson M. Tenomodulin is down-regulated in wounded and strained bioartificial equine tendons in vitro. 57th Annual Meeting of the Orthopaedic Research Society, Long Beach, CA, January 2011.
- Dmochowski J, Qi J, Banes A, Banes AJ, Smith R, Nixon A. Differential expression of tenomodulin isoforms in human tissues. 57th Annual Meeting of the Orthopaedic Research Society, Long Beach, CA, January 2011.
- Dmochowski JM, Qi J, Banes A, Bynum D, Patterson M, Banes AJ. Strain modulates tenomodulin isoform 1 expression and nuclear localization in porcine tenocytes. 57th Annual Meeting of the Orthopaedic Research Society, Long Beach, CA, January 2011.
- Qi J, Wang J, Sumanasinghe R, Wall M, Tsuzaki M, Bynum D, Banes AJ. Primary cilia are modulated by serum, interleukin-1β and strain in human tenocytes. 55th Annual Meeting of the Orthopaedic Research Society, #35, Las Vegas, NV, February 22-25, 2009.
- Qi J, Chi L, Labeit S, Banes AJ. Nuclear Localization of the Titin Z1Z2Zr Domain and Role in Regulating Cell Proliferation. (2008). Am J Physiol Cell Physiol. 295(4):C975-C985. Epub 2008 Aug 6.
- Banes AJ, Tsuzaki M, Wall M, Qi J, Yang X, Bynum D, Karas S, Hart DA, Nation A, Fox AM, Almekinders LC. The Molecular Biology of Tendinopathy: Signaling and Response Pathways in Tenocytes. In: Tendinopathy in Athletes (Volume XII of the Encyclopedia of Sports Medicine), edited by Woo S, Renstrom P, Arnoczky S. Ames, IA: Blackwell Publishing, 2007.
- Wall ME, Weinhold PS, Siu T, Brown TD, Banes AJ. Comparison of cellular strain with applied substrate strain in vitro. (2007) J Biomech 40(1):173-181. Epub 2006 Jan 5.
- Banes AJ, Qi J, Fox AM, Bynum D, Lalush D, Almekinders L. Tendon biomarkers in mouse and man: comparisons of tendon to muscle and bone and potential targets for gene therapy. In: Tendon Pathology, edited by Maffuli N, Almekinders L. Springer, 2006.
- Qi J, Fox AM, Alexopoulos LG, Chi L, Bynum D, Guiliak F, Banes AJ. IL-1b decreases the elastic modulus of human tenocytes. (2006) J Appl Physiol 101(1):189-195. Epub 2006 Apr 20.
- Qi J, Chi L, Maloney M, Yang X, Bynum D, Banes AJ. Interleukin-1b increases elasticity of human bioartificial tendons. (2006) Tissue Eng 12(10):2913-2925.
- Tsuzaki M, Bynum D, Almekinders L, Faber J, Banes AJ. Mechanical loading stimulates ecto-ATPase activity in human tendon cells. (2005) J Cell Biochem 96(1):117-125.
- Wall ME, Faber JE, Yang X, Tsuzaki M, Banes AJ. Norepinephrine-induced calcium signaling and expression of adrenoceptors in avian tendon cells. (2004) Am J Physiol Cell Physiol 287(4):C912-C918. Epub 2004 Jun 16.
- Triantafillopoulos IK, Banes AJ, Bowman KF, Maloney M, Garrett WE, Karas SG. Nandrolone decanoate and load increase remodeling and strength in human supraspinatus bioartificial tendons. (2004) Am J Sports Med 32(4):934-943.
- Banes AJ, Wall ME, Garvin J, Archambault J. Cytomechanics: signaling to mechanical load in connective tissue cells and role in tissue engineering. In: Functional Tissue Engineering, edited by Guilak F, Butler D, Goldstein R, Mooney D. New York, NY: Springer-Verlag, p. 318-334, 2003.
Dr. Mary Barbe received her B.A. in Biology from the University of North Carolina at Greensboro, and then a PhD in Anatomy from Wake Forest University in North Carolina, USA. She completed a post-doctoral fellowship in developmental neuroscience research at Medical College of Pennsylvania in Philadelphia in 1990. She is currently a Professor with tenure in the Department of Anatomy and Cell Biology at Temple University School of Medicine, in Philadelphia, PA. Dr. Barbe has received four teaching awards during her years at Temple University, including the Lindback Foundation Award for Distinguished Teaching in 2008. Dr. Barbe, in collaboration with Dr. Ann E Barr, developed a rat model of cumulative trauma disorder in which rats perform repetitive, forceful upper limb tasks. This model is used to examine the exposure-response relationship between motor task repetition rate and force and physiological and behavioral indicators of injury. Her findings have lead to studies examining biomarkers of inflammation in serum and synovial fluids of patients with overuse injuries. Dr. Barbe is currently funded by CDC-NIOSH, NIH-NIAMS, NIH- NINDS, and Foundation for Cerebral Palsy.
Some Related Publications:
Relevant Animal studies:
- Barbe MF, Barr AE, Gorzelany I, Amin M, Gaughan JP, Safadi FF. “Chronic repetitive reaching and grasping results in decreased motor performance and widespread tissue responses in a rat model of MSD.” J Orthopedic Res 21 (2003): 167-176. PMID: 12507595
- Clark BD, Barr AE, Safadi FF, Beitman L, Al-Shatti T, Amin M, Gaughan JP, Barbe MF. “Median nerve trauma in a rat model of work-related musculoskeletal disorder.” J Neurotrauma, 20 (2003): 681-695. PMID: 12908929
- Barr AE, Safadi FF, Gorzelany I, Amin A, Popoff SN, Barbe MF. “Repetitive, negligible force reaching in rats induces pathological overloading of upper extremity bones”. J Bone and Mineral Research 18 (2003): 2023-2032. PMID: 14606516
- Barr AE, Barbe MF. “Inflammation reduces physiological tissue tolerance in the development of work-related musculoskeletal disorders.” J Electromyography and Kinesiology 14 (2004): 77-85. PMID: 14759753
- Clark BD, Al-Shatti TA, Barr AE, Amin M, Barbe MF. “Performance of a high-repetition, high-force task induces carpal tunnel syndrome in rats.” J Orthop Sports Phys Ther (JOSPT) 34 (2004): 244-253. PMID: 15189016
- Barr AE, Barbe MF, Clark BD. “Work-related musculoskeletal disorders of the hand and wrist: epidemiology, pathophysiology, and sensorimotor changes. Special Issue on the Hand: Repetitive stress injuries: the pathophysiology. Invited review.” J Orthop Sports Phys Ther 34 (2004): 610-627. PMID: 15552707
- Barr AE, Barbe MF, Clark BD. “Systemic Inflammatory Mediators Contribute to Widespread Effects in Work-Related Musculoskeletal Disorders.” Exercise and Sports Sciences Reviews, 32 (2004): 135-142. PMID: 15604931
- Al-Shatti TA, Barr AE, Safadi FF, Amin M, Barbe MF. “Increase in pro- and anti-inflammatory cytokines in median nerves in a rat model of repetitive motion injury.” J Neuroimmunol. 167 (2005): 13-22. PMID: 16026858
- Barbe MF and Barr AE. “Inflammation and the pathophysiology of work-related musculoskeletal disorders.” Brain, Behavior and Immunity, 20 (2006): 423-429. PMID: 16647245
- Manns JM, Uknis AB, Rico MC, Agelan A, Castaneda J, Arango I, Barbe MF, Safadi FF, Popoff SN, and DeLa Cadena RA. “A peptide from thrombospondin 1 modulates experimental erosive arthritis by regulating connective tissue growth factor.” Arthritis Rheum. 54(2006): 2415-2422. PMID: 16869004
- Song JJ, Aswad R, Kanaan RA, Rico MC, Owen TA, Barbe MF, Safadi FF, Popoff SN. “Connective Tissue Growth Factor (CTGF) Acts as a Downstream Mediator of TGF-B1 to Induce Mesenchymal Cell Condensation.” J Cell Physiol. 210 (2007): 398-410. PMID: 17111364
- Barbe MF, Elliott MB, Abdelmagid S, Safadi FF, Popoff SN, Amin M, Barr AE. “Serum and tissue cytokines and chemokines increase with performance of repetitive upper extremity tasks.” J Orthop Res. 26( (2008): 1320-1326. PMID: 18464247
- Elliott MB, Barr AE, Kietrys DM, Amin M, Barbe MF. “Peripheral neuritis and spinal cord neurochemicals are induced in a model of repetitive motion injury with minimal force and repetition exposure.” Brain Res. 7 (2008): 1218:103-113. PMID: 18511022
- Zhu S, Barbe MF, Liu C, Hadjiargyrou M, Popoff SN, Rani S, Safadi FF, Litvin J. “Periostin-like-factor in osteogenesis.” J Cell Physiol. 218 (2009): 584-592. PMID: 19006175
- Rani S, Barbe MF†, Barr AE, Litvin J†. “The Pattern of Periostin-Like-Factor and Periostin in an Animal Model of Work-Related Musculoskeletal Disorder. “ Bone. 44 (2009): 502-512. PMID: 19095091 † Equally contributing authors.
- Elliott MB, Barr AE, Clark BD, Amin M, Amin S, Barbe MF. “High force reaching task induces widespread inflammation, increased spinal cord neurochemicals and neuropathic pain.” Neuroscience. 158 (2009): 922-931. PMID: 19032977
- Rani S, Barbe MF †, Barr AE, Litvin J†. “Induction of Periostin-Like-Factor and Periostin in Forearm Muscle, Tendon and Nerve in an Animal Model of Work-Related Musculoskeletal Disorder.” J Histochem Cytochem. 57 (2009): 1061-1073. PMID: 19620321 † equally contributing authors.
- Bove GM, Weissner W, Barbe MF. “Long Lasting Recruitment of Immune Cells and Altered Perineurial Thickness in Focal Nerve Inflammation Induced by Complete Freund’s Adjuvant.” J Neuroimmunol. 213 (2009): 26-30. PMID: 19564053
- Fedorczyk JM, Barr AE, Rani S, Amin M, Gao H, Amin S, Litvin J, Barbe MF. “Exposure dependent increases in IL-1beta, substance P, CTGF and tendinosis in flexor tendons with upper extremity repetitive strain injury.” J Orthop Res. 28 (2010): 298-307. PMID: 19743505
- Rani S, Barbe MF †, Barr AE, Litvin J†. “Role of TNF alpha and PLF in bone remodeling in a rat model of repetitive reaching and grasping.” J Cell Physiol. 225 (2010): 152-67. PMID: 20458732 † equally contributing authors.
- Elliott MB, Barr AE, Clark BD, Wade CK, Barbe MF. “Performance of a repetitive task by aged rats leads to median neuropathy and spinal cord inflammation with associated sensorimotor declines.” Neuroscience. 170 (2010): 929-941. PMID: 20673790
- Driban JB, Barr AE, Amin M, Sitler MR, Barbe MF. “Joint Inflammation and Early Degeneration Induced by High Force Reaching Are Attenuated by Ibuprofen in an Animal Model of Work-Related Musculoskeletal Disorder.” In Press for Journal of Biomedicine and Biotechnology, Special Issue: Animal Models of Human Pathology, March 2011.
Relevant Patient articles:
- Carp SJ, Barbe MF, Winter KA, Amin M, Barr AE. “Increased Cytokines and C-reactive protein in human serum are associated with severity of musculoskeletal disorders from Overuse”. Clin Sci (Lond). 112 (2007): 305-314. PMID: 17064252
- Carp SJ, Barr AE, Barbe MF. “Serum biomarkers as signals for risk and severity of repetitive stress injuries.” Biomarkers in Medicine, 2(2008): 67-79.
- Driban JB, Sitler MR, Barbe MF, Balasubramanian E. “Is osteoarthritis a heterogeneous disease that can be stratified into subsets?” Clin Rheumatol. 29(2010): 123-131. PMID: 19924499
- Driban JB, Balasubramanian E, Amin M, Sitler MR, Ziskin MC, Barbe MF. “The potential of multiple synovial-fluid protein-concentration analyses in the assessment of knee osteoarthritis.” J Sport Rehabil. 19 (2010: 411-21. PMID: 21116010
Gerald Pollack received his doctorate in biomedical engineering from the University of Pennsylvania in 1968. He then joined the University of Washington faculty and is now professor of Bioengineering.
His interests have ranged broadly, from biological motion and cell biology to the interaction of biological surfaces with aqueous solutions. His 1990 book, Muscles and Molecules: Uncovering the Principles of Biological Motion, won an “Excellence Award” from the Society for Technical Communication; his more recent book, Cells, Gels and the Engines of Life, won that Society’s “Distinguished Award.”
Pollack received an honorary doctorate in 2002 from Ural State University in Ekaterinburg, Russia, and was more recently named an Honorary Professor of the Russian Academy of Sciences. He received the Biomedical Engineering Society’s Distinguished Lecturer Award in 2002. More recently, in 2008, he was selected to receive the University of Washington’s highest singular distinction: the Annual Faculty Lecturer Award. Pollack is a Founding Fellow of the American Institute of Medical and Biological Engineering and a Fellow of both the American Heart Association and the Biomedical Engineering Society. He is also Founding Editor-in-Chief of the journal, WATER, and has recently received an NIH Transformative R01 Award.
Some Related Publications:
- Chai, B, and Pollack, GH: Solute-free interfacial zones in polar liquids. J Phys Chem B 114: 5371-5375, 2010.
- Pollack, GH: Water, energy and life: fresh views from the water's edge. Int'l J Design & Nature 5(1): 27-29, 2010.
- Shklyar, TF, Safronov, AP, Toropova, OA, Pollack, GH, and Blyakhman, FA: Mechanoelectric potentials in synthetic hydrogels: possible relation to cytoskeleton. Biophysics 55(6): 931-936, 2010.
- Klyuzhin, IS, Ienna, F, Roeder B, Wexler, A, and Pollack, GH: Persisting water droplets on water surfaces. J Phys Chem B 114: 14020-14027, 2010.
- Yoo, H, Baker, DR, Pirie, CM, Hovakeemian, B, and Pollack, GH: Characteristics of water adjacent to hydrophilic interfaces. Water: the Forgotten Molecule, pp 123-136. Ed: D LeBihan, and H Fukuyama, Pan Stanford, 2011.
- Yoo, H, Paranji, R, and Pollack, GH: Impact of hydrophilic surfaces on interfacial water dynamics probed with NMR spectroscopy. J Phys Chem Letters 2: 532- 536, 2011.
- Pollack, GH, Figueroa, X, and Zhao, Q: The minimal cell and life's origin: role of water and aqueous interfaces. The Minimal Cell: The Biophysics of Cell Compartment and the Origin of Cell Functionality. Ed: PL Luisi, and P Stano, Springer, 2011.
- Nhan, DT, and Pollack, GH: Effect of particle diameter on exclusion-zone size. In press Int'l J Design Nature, 2011.
- Shklyar, TF, Toropova, OA, Safronov, AP, Pollack, GH and Blyakhman, FA: Mechanical characteristics of synthetic polyelectrolyte gel as a physical model of the cytoskeleton. Biophysics 56(1): 68-73, 2011.
- Figueroa, X, and Pollack, GH: Exclusion-Zone formation from discontinuous Nafion surfaces. In press Design and Nature, 2011.
- O'Rourke, C, Klyuzhin, IS, Park, JS and Pollack, GH: Unexpected water flow through Nafion-tube punctures. Phys Rev E 83(5), 2011.
Dr. Kjaer was educated as a Medical doctor from University of Copenhagen in 1984, and became a Specialist in Rheumatology in 1995. He is Head of Institute of Sports Medicine, Dept of Orthopedic Surgery, Bispebjerg Hospital in Copenhagen and Clinical Professor in Sports Medicine at University of Copenhagen, Denmark. Dr. Kjaer’s research group focuses on adaptation of tendon and skeletal muscle to mechanical loading and physical training, with special emphasize on physiological-pathological adaptation to overloading and regeneration of tissue. He has published more that 250 original papers and supervised more than 20 PhD students and 5 post doctoral students.
Some Related Publications:
- Heinemeier KM, Olesen JL, Haddad F, Langberg H, Kjaer M, Baldwin KM, Schjerling P. Expression of collagen and related growth factors in rat tendon and skeletal muscle in response to specific contraction types. J.Physiol. 582: 1303-1306, 2007.
- Magnusson SP, Narici MV, Maganaris CN, Kjaer M. Human tendon behaviour and adaptation, in vivo. J.Physiol. 586: 71-81, 2008.
- Haraldsson BT, Aagaard P, Qvortrup K, Bojsen-Møller J, Krogsgaard M, Koskinen S, Kjaer M, Magnusson SP. Lateal force transmission between human tendon fascicles. Matrix Biol. 27: 86-95, 2008.
- Hansen M, Kongsgaard M, Holm L, Skovgaard D, Magnusson SP, Qvortrup K, Larsen JO, Dahl M, Serup A, Frystyk J, Flyvbjerg A, Langberg H, Kjaer M. Effect of estrogen on tendon collagen synthesis, tendon structure characteristics, and biomechanical properties in postmenopausal women. J.Appl.Physiol. 106: 1385-1393, 2009.
- Couppe C, Hansen P, Kongsgaard M, Kovanen V, Suetta C, Aagaard P, Kjaer M, Magnusson SP. Mechanical peroperties and collagen cross-linking of the patellar tendon in old and young men. J Appl Physiol 107: 880-886, 2009.
- Mikkelsen UR, Langberg H, Helmark IC, Skovgaard D, Andersen LL, Kjaer M, Mackey AL. Region specific prostaglandin blockade inhibits satellite cell proliferation in human skeletal muscle following eccentric exercise. J. Appl. Physiol. 107: 1600-1611, 2009.
- Holm L, Hall GV, Rose AJ, Miller BF, Doessing S, Richter EA, Kjaer M. Contraction intensity and feeding affect collagen and myofibrillar synthesis rates differently in human skeletal muscle. Am J Physiol (Endo), 298: E257-E269, 2010.
- Doessing S, Heinemeier KM, Holm L, Mackey AL, Schjerling P, Rennie MJ, Smith K, Reitelseder S, Kappelgaard AM, Højby Rasmussen M, Flyvbjerg A, Kjaer M. Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis. J.Physiol. 588: 341-351, 2010.
- Bayer ML, Yeung CY, Kadler KE, Qvortrup K, Baar K, Svensson RB, Magnusson SP, Krogsgaard M, Koch M, Kjaer M. The initiation of embryonic-like collagen fibrillogenesis by adult human tendon fibroblasts when cultured under tension. Biomaterials 31: 4889-4897, 2010.
- Magnusson SP, Langberg H and Kjaer M. Pathogenesis of tendinopathy - the balance between healthy and injurious adaptation to loading. Nature Rev Rheum, 5: 262-268, 2010.
Professor Reed’s holds and MD and a PhD and his research area is microcirculatory exchange with a particular focus on inflammatory processes and how the loose connective tissues can modify this exchange. Together with researchers at Uppsala University in Sweden he has demonstrated that the loose connective tissues during inflammatory edema contribute markedly to the rapid edema development and that this edema process can be manipulated pharmacologically.
Professor Reed is currently Head of Department of Department of Biomedicine, Norway since 2005. He has been Chairman of the Board of Medicine and Health in the Research Council of Norway and has participated in several national and international review panels and boards.
Some Related Publications:
- K. Aukland and R. K. Reed. Interstitial-lymphatic control of extracellular fluid volume. Physiological Reviews 73: 1-78, 1993.
- R. K. Reed, Å. Lidén and K. Rubin. Edema and fluid dynamics in connective tissue remodelling. Journal of Molecular and Cellular Cardiology 48: 518-523, 2010.
- R. K. Reed and K. Rubin. Transcapillary exchange: Role and importance of the interstitial pressure and the extracellular matrix. Cardiovascular Research 87:211-7, 2010.
Original research articles.
- R. K. Reed, K. Rubin, H. Wiig and H. Rodt. Blockade of ß1-Integrins in skin causes edema through lowering of interstitial fluid pressure. Circulation Research 71: 978-983, 1992.
- K. Woie, M.-E. Koller, K Heyeraas and R. K. Reed. Neurogenic inflammation in rat trachea is accompanied by increased negativity of interstitial fluid pressure. Circulation Research. 73: 839-845, 1993.
- S. Å. Rodt, R. K. Reed, M. Ljungström, T.O. Gustafsson and K. Rubin. The anti-inflammatory agent α-trinositol exerts its edema preventing effect through modulation of ß1 integrin function in rats. Circulation Research 75: 942-948, 1994.
- S. Å. Rodt, K. Åhlèn, A. Berg, K. Rubin and R. K. Reed. A novel function for platelet-derived growth-factor BB in rat dermis. Journal of Physiology 495: 193-200, 1996.
- Berg, K. Åhlen, K. Rubin, J. Stjernschantz and R. K. Reed. Effect of PGE1, PGI2, and PGF2α on collagen gel compaction in vitro and interstitial fluid pressure in vivo. American Journal of Physiology 274 (Heart and Circulatory Physiology 43): H663-H671, 1998.
- K. Pietras, A. Östman, M. Sjöquist, E. Buchdunger, R. K. Reed, C.-H. Heldin. The selective PDGF receptor kinase inhibitor STI571 reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Research 61: 2929-2134, 2001.
- T. Nedrebø R. K. Reed and A. Berg. Effect of a-trinostol on interstitial fluid pressure, edema-formation and albumin extravasation after ischemia-reperfusion in rat hind-limb. Shock 20: 149-153, 2003.
- T. Nedrebø, T. V. Karlsen, G. S. Salvesen and R. K. Reed, A novel function for insulin in rat dermis. Journal of Physiology 559: 583-291, 2004.
- Å. Lidèn, A. Berg, T. Nedrebø, R. K. Reed and K. Rubin. PDGF BB-mediated normalization of dermal interstitial fluid pressure after mast cell degranulation depends on b3, but not b1-integrins. Circulation Research 98: 635-641, 2006.
- Å. Oldberg, S. Kalamajskij, A. Salnikov, L. Stuhr, M. Mörgelin, R. K. Reed, N.-E. Heldin and K. Rubin. The small leucine-rich repeat proteoglycan fibromodulin determines stroma structure and physiology in experimental carcinoma. Proceedings National Academy of Sciences 104: 13966-13971, 2007
- Ø. S. Svendsen, Å. Lidén, T. Nedrebø, K. Rubin and R. K. Reed. Integrin aVb3 acts downstream in normalization of interstitial fluid pressure in sepsis and in cell-mediate collagen cell contraction. American Journal of Physiology (Heart and Circulatory Physiology) 295: H555-H560, 2008.
- Ø. S. Svendsen, Å. Lidén, K. Rubin and R. K. Reed. Lowered albumin extravasation rate in heart, but not in other organs in beta3-integrin deficient mice. Acta Pysiologica Scandnavica 197: 305-311, 2009
Dr. Shah is a senior staff physiatrist and investigator in the Rehabilitation Medicine Department at the Clinical Center of the National Institutes of Health in Bethesda, Maryland USA. His clinical research interests include the pathophysiology of myofascial pain and the integration of physical medicine techniques with promising complementary approaches in the management of neuro-musculoskeletal pain and dysfunction. Dr. Shah is a well-known lecturer on the mechanisms of chronic pain, myofascial pain, acupuncture techniques and other related topics. Dr. Shah and his co-investigators at the NIH are utilizing novel microanalytical and ultrasound imaging techniques to study the unique biochemical milieu and viscoelastic properties of myofascial trigger points and surrounding soft tissue. His research has been published in the Journal of Applied Physiology, Archives of Physical Medicine and Rehabilitation, and the Journal of Bodywork and Movement Therapies. Dr. Shah also teaches hands-on workshops for physicians, dentists and physical therapists among others. His workshops integrate emerging knowledge from the clinical pain sciences in order to improve evaluation and management approaches to musculoskeletal pain and dysfunction. Dr. Shah was selected by the American Academy of Pain Management as the 2010 recipient of the Janet Travell Clinical Pain Management Award.
Some Related Publications:
- Sikdar S, Ortiz R, Gebreab T, Gerber LH, Shah JP. Understanding the vascular environment of myofascial trigger points using ultrasonic imaging and computational modeling. Conference Proceedings Institute of Electrical and Electronics Engineers, Engineering in Medicine and Biology Society 2010;1:5302-5.
- Sikdar S, Shah JP, Gebreab T, et al. Novel applications of ultrasound technology to visualize and characterize myofascial trigger points and surrounding soft tissue.Arch Phys Med Rehabil 2009; 90:1829-1838.
- Sikdar S, Shah JP, Gilliams E, Gebreab T, Gerber LH. Assessment of myofascial trigger points (MTrPs): a new application of ultrasound imaging and vibration sonoelastography.Conf Proc IEEE Eng Med Biol Soc 2008; 2008:5585-5588.
- Shah JP, Gilliams EA. Uncovering the biochemical milieu of myofascial trigger points using in-vivo microdialysis: An application of muscle pain concepts to myofascial pain syndrome. Journal of Bodywork and Movement Therapies. 2008; 12(4): 371-84
- Shah JP, Danoff JV, Desai MJ, et al. Biochemicals associated with pain and inflammation are elevated in sites near to and remote from active myofascial trigger points.Arch Phys Med Rehabil 2008; 89:16-23.
- Shah, J.P., 2008. Integrating dry needling with new concepts of myofascial pain, muscle physiology, and sensitization. In: Audette, J.F., Bailey, A. (Eds.), Integrative Pain Medicine: The Science and Practice of Complementary and Alternative Medicine in Pain Management. Humana Press, Totowa, pp. 107-121
- Shah JP, Phillips TM, Danoff JV, Gerber LH. An in vivo microanalytical technique for measuring the local biochemical milieu of human skeletal muscle.J Appl Physiol 2005; 99:1977-1984.
- Dommerholt J, Shah JP. Myofascial pain syndrome. In: Fishman SF, Ballantyne JC, Rathmell JP, (Eds). Bonica’s Management of Pain, 4th ed. Philadelphia: Lippincott Williams & Wilkins, 2010; 450-471.
Dr. Sherman is an epidemiologist and Senior Investigator at the Group Health Research Institute in Seattle and holds an affiliate appointment at the University of Washington. Since 1996, her research has focused on evaluating complementary and alternative treatments for musculoskeletal conditions and other common health problems. Dr. Sherman has lead or collaborated on over a dozen NIH funded randomized clinical trials of complementary medical (CAM) therapies, including six clinical trials of massage. She has published widely in the area of CAM and is well known as an expert on the design and conduct of clinical trials of CAM. Dr. Sherman regularly lectures nationally and internationally to scientific and CAM audiences on her research and on the methods for studying CAM therapies. She acts as a reviewer for dozens of medical journals and sits on the editorial board for International Journal of Yoga Therapy and Focus on Alternative and Complementary Therapies and is a Methodology Editor for Alternative Therapies in Health and Medicine. Dr. Sherman recently chaired the Scientific Advisory Board for the conference "Highlighting Massage Therapy in CIM Research".
Some Related Publications:
- Cherkin DC, Eisenberg D, Sherman KJ, Barlow W, Kaptchuk TJ, Street J, Deyo RA. A randomized trial comparing Traditional Chinese Medical Acupuncture, Therapeutic Massage and Self-Care education for chronic low back pain. Arch Intern Med 2001;161:1081-8.
- Sherman KJ, Cherkin DC, Kahn J, Erro J, Hrbek A, Deyo RA, Eisenberg DM. The Practice Of Massage Therapy: A Survey Of Massage Therapists And Their Practices In Two US States BMC Complementary and Alternative Medicine 2005; 5:13.
- Sherman KJ, Dixon MW, Thompson D, Cherkin DC. Development of a taxonomy to describe massage treatments for musculoskeletal pain. Biomed Central Complementary and Alternative Medicine 2006;6: 24.
- Sherman KJ, Cherkin DC, Hawkes R, Miglioretti DL, Deyo RA. Randomized Controlled Trial of Massage versus Self-care for Chronic Neck Pain. Clinical Journal of Pain 2009; 25: 233-238.
- Sherman KJ, Ludman EJ, Cook AJ, Hawkes RJ, Roy-Byrne PP, Bentley S, Brooks M, Cherkin DC. Randomized trial of therapeutic massage for Generalized Anxiety Disorder. Depression and An
Dr. Stecco is currently Assistant Professor of Human Anatomy and Movement Sciences at the University of Padova, Italy. She is a founding member of the Fascial Manipulation Association and a member of the Italian Society of Anatomy and Histology and of the Association Française des Morphologistes. Dr. Stecco’s scientific activity is devoted to the study of the anatomy of the human fasciae from a macroscopical, histological and physiopathological point of view. She personally made over 100 dissections of fresh cadavers for research. From 2000, Dr. Stecco organizes and personally holds theoretical-practical courses on the Fascial Manipulation technique both in Italy and in other countries. She is the author of more than forty in extenso papers on fascial anatomy, all indexed in PubMed. She is also the author of Manipolazione Fasciale, Piccin, 2007, translated into English, Fascial Manipulation: practical part. Piccin, 2009
Some Related Publications:
- Benetazzo Luigino, Bizzego Andrea, De Caro Raffaele, Frigo Guglielmo, Guidolin Diego, Stecco Carla “3D reconstruction of the crural and thoracolumbar fasciae” Surgical and Radiololigal Anatomy Jan 4 (2011), [Epub ahead of print],
- Borgini Ercole, Stecco Antonio, Day Julie Ann, Stecco Carla “How much time is required to modify a fascial fibrosis?” Journal of Bodywork and Movement Therapies (2010) 14: 318-25.
- Stecco Carla, Macchi Veronica, Lancerotto Luca, Tiengo Cesare, Porzionato Andrea, De Caro Raffaele “Comparison of Transverse Carpal Ligament and Flexor Retinaculum Terminology for the Wrist” Journal of Hand Surgery American. (2010) 35(5):746-53.
- Stecco Carla, Macchi Veronica, Porzionato Andrea, Morra Aldo, Parenti Anna, Stecco Antonio, Delmas Vincent, De Caro Raffaele. “The Ankle Retinacula: Morphological Evidence of the Proprioceptive Role of the Fascial System.” Cells Tissues Organs (2010) 192(3):200-10.
- Natali Arturo, Pavan Piero, Stecco Carla “A constitutive model for the mechanical characterization of the plantar fascia.” Connective Tissue Research (2010) 51(5):337-46.
- Macchi Veronica, Tiengo Cesare, Porzionato Andrea, Stecco Carla, Vigato Enrico, Parenti Anna, Azzena Bruno, Weiglein Andreas, Mazzoleni Francesco, De Caro Raffaele “Histotopographic study of the fibroadipose connective cheek system.” Cells Tissues Organs (2010) 191(1): 47-56.
- 7: Day Julie Ann, Stecco Carla, Stecco Antonio “Application of Fascial Manipulation technique in chronic shoulder pain--anatomical basis and clinical implications.” Journal of Bodywork and Movement Therapies (2009) 13(2):128-35.
- Stecco Carla, Pavan Piero, Porzionato Andrea, Macchi Veronica, Lancerotto Luca, Carniel Emanuele, Natali Arturo, De Caro Raffaele “Mechanics of crural fascia: from anatomy to costitutive modelling” Surgical and Radiological Anatomy (2009) 31(7): 523-9.
- Pedrelli Alessandro, Stecco Carla, Day Julie Ann “Treating patellar tendinopathy with Fascial Manipulation.” Journal of Bodywork and Movement Therapies (2009) 13(1):73-80. Epub 2008 Jul 26. PubMed PMID: 19118795.
- Stecco Antonio, Macchi Veronica, Stecco Carla, Porzionato Andrea, Day Julie Ann, Delmas Vincent, De Caro Raffaele “Anatomical study of myofascial continuity in the anterior region of the upper limb.” Journal of Bodywork and Movement Therapies (2009) 13(1): 53-62. Epub 2007 Jun 28. PubMed PMID: 19118793.
- Stecco Carla, Porzionato Andrea, Lancerotto Luca, Stecco Antonio, Macchi Veronica, Day Julie Ann, De Caro Raffaele “Histological study of the deep fasciae of the limbs.” Journal of Bodywork and Movement Therapies (2008) 12(3):225-30. Epub 2008 Jun 13. PubMed PMID: 19083678.
- Stecco Antonio, Macchi Veronica, Masiero Stefano, Porzionato Andrea, Tiengo Cesare, Stecco Carla, Delmas Vincent, De Caro Raffaele “Pectoral and femoral fasciae: common aspects and regional specializations” Surgical and Radiological Anatomy (2009) 31(1): 35-42.
- Stecco Carla, Porzionato Andrea, Macchi Veronica, Stecco Antonio, Vigato Enrico, Parenti Anna, Delmas Vincent, Aldegheri Roberto, De Caro Raffaele “The expansions of the pectoral girdle muscles onto the brachial fascia: morphological aspects and spatial disposition” Cells Tissues Organs. (2008) 188 (3): 320-329.
- Stecco Carla, Gagey Olivier, Belloni Anna, Pozzuoli Assunta, Porzionato Andrea, Macchi Veronica, Aldegheri Roberto, De Caro Raffaele, Delmas Vincent “Anatomy of the deep fascia of the upper limb. Second part: study of innervation”. Morphologie (2007) 91(292): 38-43. PubMed PMID: 17574469.